How can I get Asymmetric Waveform Ion Mobility Spectrometry for my mass spectrometer?
Two companies have a commercial interest in FAIMS for mass spectrometry. Some information is presented here for Thermo Scientific and for Agilent Technologies. More details at their respective web sites.
I. Thermo Scientific.
A FAIMS for mass spectrometry may be acquired from Thermo Scientific. Details
Thermo Fisher Scientific adds FAIMS Capability to Ion Trap Mass Spectrometers: Precise and reliable results for proteomics and metabolism analyses
Thermo Fisher Scientific, the world leader in serving science, announces that the Thermo Scientific FAIMS (high-Field Asymmetric waveform Ion Mobility Spectrometry) interface is now available for the Thermo Scientific industry-leading family of ion trap mass spectrometers. The FAIMS capability eliminates interferences and significantly increases the number of the total spectra that match sequences and eliminates the need for additional time-consuming separation steps. Well-suited for proteomics applications, as much as 90% of the total FAIMS spectra have been shown to match peptide sequences.
The combination of FAIMS and ion trap mass spectrometers addresses the needs of scientists working in laboratories who require more definitive results and multiple modes of separation from interferences.
Thermo Scientific ion trap mass spectrometers, when coupled with the FAIMS interface, allow users to selectively isolate target compounds based on a number of physical properties, including charge state and molecular conformation. This selection of ions occurs before the introduction of the sample into the mass spectrometer, reducing background noise, increasing selectivity and improving spectral quality.
For more information about the combined FAIMS-Ion Trap MS platform please call +1 800-532-4752, e-mail analyze@thermofisher.com or visit www.thermo.com/faims
II. Agilent Technologies
Owlstone and Agilent Technologies Collaborate to Explore FAIMS/TOF-MS Applications
PHILADELPHIA, ASMS June 1, 2009
Owlstone Nanotech Inc., a subsidiary of Advance Nanotech Inc. (OTCBB: AVNA), and Agilent Technologies Inc. (NYSE: A) today announced a phase one agreement to develop Owlstone's field-asymmetric ion mobility spectrometry (FAIMS) filter as a front-end separation module for Agilent's Accurate Mass time-of-flight mass spectrometers (TOF-MS).
The goal is to determine how the systems can work together to enable identification of previously unresolved analytes. The collaboration will also explore how FAIMS can speed up liquid chromatographic separations, saving valuable analysis time.
"The collaboration with Agilent gives us the opportunity to integrate our technology onto highly sensitive mass spectrometers that are ideal for demonstrating the benefit of the uniquely high-field, fast scanning ability of our FAIMS device," said Bret Bader, Owlstone CEO. Partnerships with highly-skilled organizations like Agilent are a key part of our business strategy. We view this alliance with a recognized industry leader as a further stride in the realization of this strategy and a testament to the quality we strive to achieve at Owlstone; and we are very excited by the potential of these collaborative efforts to bring new analytical capabilities to a world-wide market."